Current functions                             

1997 – 2011 orthopaedic surgeon/head of department; Tergooiziekenhuizen
(Official training facility for orthopaedic surgeons)
since 2010 orthopedic surgeon; AVE-Orthopedische klinieken, Huizen
kneesurgery, spinesurgery, pediatric orthopaedics and implantology   

Prev functions                    

captain/doctor orthopaedic department, nederlandse landmacht
1987-1988 Militair Hospitaal Dr A. Mathijsen, Utrecht
general surgery training

1988-1991 Mariastichting/Spaarne Ziekenhuis, Haarlem
orthopaedics training

1991-1995 Academic Medical Centre, Amsterdam
(Prof. Dr R.K. Marti)
staffmember orthopedic department

1995-1997 Academisch Medisch Centrum

PhD Thesis

“Wear, particles and physical factors in loosening of hip prostheses”
1997 Promotores: R.K.Marti, C.J.F. van Noorden
Co promotor: P. Aspenberg

Papers                                  

“Benign cellular responses in rats to different wear particles in intra-
articular and intramedullary invironments”
Journal of Bone and Joint Surg (B), 79(5): 837-843 (1997)

“Fluid pressure causes bone resorption in a rabit model of prosthetic
loosening”
Clin Orthop and Rel Res 350: 201-208 (1998)

“Short periods of oscillating fluid pressure directed at a bone –titanium
interface leads to bone lysis”
Acta Orthop Scand 69(1): 5-10 (1998)

“Fluid pressure may cause periprosthetic loosening: particles are not the
only thing”
Acta Orthop Scand 69(1): 1-4 (review) (1998)

“Migration, particles and fluid pressure. A discussion of causes of
prosthetic loosening”
Clin Orthop and Rel Res 352: 75-80 (1998)

“Socket wear in ceramic-on-polyethylene total hip arthroplasties:
Fixed versus rotating heads”
Acta Orthop Scand 69(3): 248-252 (1998)

“Mechanical compression of a fibrous membrane surrounding bone
causes bone resorption”
Acta Histochemica 101(2): 203-212 (1999)

“Kniearthroskopien bei höllandischen Patienten des hohen
Lebensalters” Rutten, Patt, Raven, van der Vis, Albers
Z Orthop Unfall 2003; 141

“Trochanteric reduction osteotomy as a treatment for refractory
trochanteric bursitis” Govaert, van der Vis, Marti, Albers
J Bone Joint Surg Br. 2003 Mar;85(2):199-203            

                               
“The Weber rotation total hip prosthesis: a five to twenty year followup
study” (de Jong, van der Vis, de Man en Marti)
Clin Orthop and Rel Research 2004 feb 419; 107-114

“Effects of mechanical compression of a fibrous membrane with or without the
presence of high density polyethylene particles in a rabbit model of                                                                          prosthetic loosening”(de Man, Marti, van Noorden, van der Vis)
Journal of Bone and Joint Surgery Am. 2005 Jul;87(7): 1522-33

“Total Hip replacement with superolateral bonegrafting for osteoartritis
secondary to dysplasia” (de Jong, Marti, van der Vis)
Journal of Bone ands Joint Surg Br 2006 Feb; 88(2):173-8

“Occlusion of the posterior tibial artery after pantalar arthrodesis”
Taualadan, Koedam, Pels-Rijcken, van der Vis
Acta Orthop Scand 2007; 78(3): 442

“Arthroscopic debridement for grade III and IV Chondromalacia of the knee in patients older than 60 years” (Bekerom vd M, Patt T,Rutten S,Raven E,Vis vd H, Albers GHR) J Knee Surg 2007 20 4

“ Early complications after HTO; comparison of two techniques” (Bekerom,
MPJ vd, Patt TW, Kleinhout MY, Vis HM vd, Albers GHR
J Knee Surg 2008 Jan;21(1):68-74.

“ Small stem total Hip Arthroplasty in hypoplasia of the femur " (de Man, Haverkamp,
van der Vis, Besselaar, Marti) Clin Orthop and Rel Res 466, 6, june 2008

“ Clinical and experimental aspects of fixation, loosening and revison of cemented  total hip arthroplasty”. Copromotor of double-thesis with H.de Man and P.T. de Jong, february 2009.
“Polyethylene wear particles do not induce inflammation or gelatinase (MMP-2 and MMP-9) activity in fibrous tissue interfaces of loosening total hip arthroplasties” : Acta Histochemica 113 (2011), pp 556-563

“Acute compartment syndrome of the thigh following total knee arthroplasty” (R.H.
Boonstra, M.M. Campo, dr. D. Haverkamp, dr. H.M. van der Vis) The knee,
2011 in press

"Obesity in Total Hip Arthroplasty, does it really matter? A meta-analysis." Haverkamp, et al, van der Vis. Acta Orthop Scand 2011 in press “Venous thromboembolism prophylaxis after total knee or hip replacement - treatment pattern and outcomes”, Pharmacoepidem. and Drug Safety, accepted 2011

“Treatment of an osteoporotic vertebral compression fracture with the StaXx FX procedure resulting in intrathoracic wavers” Plaat, Bulstra, Albers, Eerenberg, van der Vis. Spine, accepted 2011

“Early loosening of a press fit cup with ceramic on ceramic articulation: our early results” Haverkamp, et al, van der Vis.  Submitted 2011, Acta Orthop Scand

Studies performed as Primairy Investigator

EEST

Sponsor: Ortho biotech
Open randomised study to evaluate the effect of peri-operative treatment of anaemia with epoetin alfa on peri-operative Hb, the incidence of allogeneic blood transfusions, postoperative infections and recovery compared to tandard of care in patients undergoing major elective orthopedic surgery.
Study number: PRI/EPO-INT-52
Start: jul. 2000 End: may 2001
In: Eur J Anaesthesiol. 2005 Apr;22(4):249-57.
Effects of epoetin alfa on blood transfusions and postoperative recovery in orthopaedic surgery: the European Epoetin Alfa Surgery Trial (EEST).

EXPERT
Sponsor: Sanofi-synthelabo
Fondaparinux sodium (ARIXTRA®) use in daily practice in patients undergoing major orthopedic surgery of the lower limbs.
Study number: C8843
Start : sept. 2003 End : oct. 2004
In: Anesthesia and Analgesia. 2007 Dec;105(6):1540-7,
The safety and efficacy of extended thromboprophylaxis with fondaparinux after major orthopedic surgery of the lower limb with or without a neuraxial or deep peripheral nerve catheter: the EXPERT Study.

ODIXAHIP
Sponsor: Bayer health care
Controlled, Double-blind, Randomised, Dose-ranging Study on the prevention of VTE in patients undergoing Elective Total Hip Replacement-ODIXaHip HIP Study
Study number: 10944
Start: jan. 2004 End: oct. 2004
In: Circulation. 2006 Nov 28;114(22):2374-81. Epub 2006 Nov 20.
A once-daily, oral, direct Factor Xa inhibitor, rivaroxaban (BAY 59-7939), for thromboprophylaxis after total hip replacement.

ODIXAHIP-OD
Sponser: Bayer health care
Controlled, Double-blind, Randomised, Dose-ranging Study of once-daily regimen of BAY 59-7939 in the prevention of VTE in patients undergoing elective total hip replacement ODIXaHIP-OD.
Study number: 11527
Start: oct 2004 End: sep 2005

RECORD 1
Sponsor Bayer Health care
RECORD 1 study: Regulation of coagulation in orthopedic surgery to prevent DVT end PE, controlles, double-blind, randomized study of BAY 59/7939 in the ectended prevention in patients undergoing elective total hip replacement.
Study number 11354
Start: feb. 2006 End: apr. 2007
In: New Engl J Med. 2008 Jun 26; 358(26): 2765-75
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty.  

RECORD 3
Sponser: Bayer health care
RECORD 3 Study: Regulation of Coagulation in Orthopedic Surgery to Prevent DVT and PE; a controlled, double-blind, randomized study of BAY 59-7939 in the prevention of VTE in subjects undergoing elective total knee replacement.
Study number: 11356
Start : feb. 2006 End: apr. 2007
In: New Engl J Med. 2008 Jun 26; 358(26): 2776-86
Rivaroxaban versus enoxaparin for thromboprophylaxis after knee arthroplasty.  

SANGART
Sponser: Quitiles
A multi-centre, randomized, double blind, controlled Phase II study of the  efficacy and safety of an oxygen-carrying colloid and plasma expander, Hemospan®, compared with colloid (Voluven®) for treatment of  perioperative hypotension in patients undergoing primary hip arthroplasty  with spinal anesthesia.
Start: aug. 2007 End: aug. 2008

XAMOS  
Sponsor: Bayer HealthCare
Xarelto® in the prophylaxis of post surgical venous tromboembolism after elective major orthopedic surgery of hip or knee
Start: may 2007 End dec. 2010

Abstracts                             

“High liquid pressure causes bone resorption in an animal model of aseptic loosening”
Acta Orthop Scand 68 (Suppl 277): 9-10

“Wear particles and physical factors in loosening of hip prostheses”
Acta Orthop Scand 68 (Suppl 277): 90-91

“Fluid pressure directed at a bone-titanium interface in rabbits leads to
bone lysis”
Journal of Orthopaedic Research 1998

“Benign cellular responses to different wear particles in intra-articular
and intramedullar environments in rats”
Journal of Bone and Joint Surg (B) 1999, 81 (suppl 1): 51

Oral presentations             

“High liquid pressure causes bone resorption in an animal model
of aseptic loosening”
Huiskes symposium NOV jaarvergadering 1997

“Benign cellular responses to different wear particles in intra-articular
and intramedullar environments in rats”
EORS, Barcelona, Spain 1997

“Particles and fluid pressure in loosening of hip prostheses”
Lund, Sweden jan 1998

“Fluid pressure directed at a bone-titanium interface in rabbits leads to
bone lysis”
ORS, New Orleans, USA feb 1998

“Socket wear in ceramic-on-polyethylene THR”
Symposium metal-on-metal THR, Brussels, Belgium 1998

“Weber Rotationsprothesen und HDPE verschleiss”
Hip symposium, Hamburg, Germany 1999

“De rol van lokale hoge vloeistofdruk in periprosthetischebotresorptie”
NOV jaarvergadering, Rotterdam 2000

“A collar has no function” minibattle European Symposium on Hip
Replacement; May 2002; Lyon, France

“The Weber Total Hip replacement” European Hip Course; November
2002; Zurich, Switserland

“ Posterior stabilized knee design” CE 2003 Zurich
“ Knieendoprotetik: Posterior Stabilized” 2004 Leipzig
“ Modularity, the key to succes in TKR” EFORT 2005; Lissabon
“ Live surgery in the difficult primary TKR”
Symposium TKR Hilversum, april 2006

“ Behandeling van osteoporotische wervelfracturen”
Symposium osteoporose Hilversum; june 2006

" Revision Uni to Total Knee arthroplasty: a total solution?"
Uniknee symposium Hilversum october 2008

“Glucosamine minibattle”
Early knee arthritis, Huizen, october 2010

Poster                                   

“Bone resorption by fluid pressure in a rabbit model of prosthetic
loosening” EORS, Barcelona, Spain 1997   

GCP                                      

“GCP training sept 2004”                                                                               
july 2011